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KMID : 1141920240400010003
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Annals of Coloproctology
2024 Volume.40 No. 1 p.3 ~ p.12
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Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery
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Jingting Wu
Hannah Chi
Shawn Kok
Jason M.W. Chua
Xi-Xiao Huang
Shipin Zhan
Shimin Mah
Li-Xin Foo
Hui-Yee Peh
Hui-Bing Lee
Phoebe Tay
Cherie Tong
Jasmine Ladlad
Cheryl H.M. Tan
Nathanelle Khoo
Darius Aw
Cheryl X.Z. Chong
Leonard M.L. Ho
Sharmini S. Sivarajah
Jialin Ng
Winson J.H. Tan
Fung-Joon Foo
Bin-Tean Teh
Frederick H. Koh
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Abstract
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Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass and strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, postoperative sepsis, prolonged length of stay, increased cost of care, decreased functional outcome, and poorer oncological outcomes in cancer surgery. Multimodal prehabilitation, as a concept that involves boosting and optimizing the preoperative condition of a patient prior to the upcoming stressors of a surgical procedure, has the purported benefits of reversing the effects of sarcopenia, shortening hospitalization, improving the rate of return to bowel activity, reducing the costs of hospitalization, and improving quality of life. This review aims to present the current literature surrounding the concept of sarcopenia, its implications pertaining to colorectal cancer and surgery, a summary of studied multimodal prehabilitation interventions, and potential future advances in the management of sarcopenia.
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KEYWORD
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Colorectal surgery, Sarcopenia, Preoperative exercise, Nutritional therapy, Frailty
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